CD47 Polyclonal Antibody-NCP0212P

CD47 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0212P-50, NCP0212P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q08722

Host: Rabbit

Reactivity: Human

Applications: WB, IF

All Applications: WB: 1:1000~1:2000
IF 1:50~1:200

Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity).Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD47 polyclonal antibody detects endogenous levels of CD47 protein.

Bioworld Molecular Weight: ~45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD47 polyclonal antibody at 1:1000 dilution
Lane 1: MCF-7 cell membrane lysate (25ug)
Lane 2: SGC7901 cell membrane lysate (25ug), Immunofluorescence analysis of MCF-7 cells using CD47 pAb at dilution of 1:200.

Alternative Name: Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD47

Immunogen: Recombinant protein of human CD47.

Conjugate: Unconjugated

Modification: Unmodified