CD49D Monoclonal Antibody - BT-MCA4307

CD49D Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4307-50, BT-MCA4307-100

Citations, Manuals and MSDS Available upon request.

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: CD49D

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7E4C5

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CD49D

Immunogen: Purified recombinant fragment of human CD49D (AA: extra 833-977) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 114.9kDa

UniProt Accession: P13612

Synonyms: ITGA4, IA4

GeneID: 3676

Research Use Only