Product Description

CD49f Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66935-50, MB66935-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities . Integrins not only transmit signals to cells in response to the extracellμlar environment , but also sense intracellμlar cues to alter their interaction with the extracellμlar environment . Integrin α6 is a 120 kDa protein with two splice variants, integrin α6, 6A and 6B , which function as receptors for laminins on the basal membrane to mediate cellμlar adhesion events . α6 integrins have been shown to play an important role in hematopoietic stem and progenitor cell homing to the bone marrow.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC, IF/ICC, FC

Alternate Names: Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human CD49f. The exact sequence is proprietary.

Dilution: WB (1/1000 - 1/5000), IHC (1/50 - 1/200), IF/ICC (1/10 - 1/50), FC (1/10 - 1/50)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of CD49f protein.

Molecular Weight: ~ 130 kDa

Pathway: Regμlation of Actin Dynamics, G Protein-coupled Receptors Signaling to MAPK Erk, PI3K AKT signaling

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P23229

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only