CD53 Monoclonal Antibody - BT-MCA3288

CD53 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3288-50, BT-MCA3288-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

Research Areas: Immunology

Target Protein: CD53

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1H2C7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD53

Immunogen: Purified recombinant fragment of human CD53 (AA: extra mix) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 24.3kDa

UniProt Accession: P19397

Synonyms: MOX44, TSPAN25

GeneID: 963

Research Use Only