Product Description

CD6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: NCP0218P-50, NCP0218P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cell adhesion molecμle that mediates cell-cell contacts and regμlates T-cell responses via its interaction with ALCAM/CD166.Contributes to signaling cascades triggered by activation of the TCR/CD3 complex.Functions as costimμlatory molecμle, promotes T-cell activation and proliferation.Contributes to the formation and maturation of the immunological synapse.Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria.LPS binding leads to the activation of signaling cascades and down-stream MAP kinases.Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.

Category: Primary Antibody

Reactivity: Rat, Mouse, Human

Host: Rabbit

Applications: WB, IF

Alternate Names: T-cell differentiation antigen CD6, T12, TP120, CD6, Soluble CD6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of human CD6.

Dilution: WB: 1:1000~1:2000
IF 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD6 polyclonal antibody detects endogenous levels of CD6 protein.

Molecular Weight: ~ 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P30203

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only