Product Description

CD6 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0218P-50, NCP0218P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P30203

Host: Rabbit

Reactivity: Rat, Mouse, Human,

Applications: WB, IF

All Applications: WB: 1:1000~1:2000
IF 1:50~1:200

Background: Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166.Contributes to signaling cascades triggered by activation of the TCR/CD3 complex.Functions as costimulatory molecule; promotes T-cell activation and proliferation.Contributes to the formation and maturation of the immunological synapse.Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria.LPS binding leads to the activation of signaling cascades and down-stream MAP kinases.Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD6 polyclonal antibody detects endogenous levels of CD6 protein.

Bioworld Molecular Weight: ~ 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD6 polyclonal antibody at 1:1000 dilution
Lane 1: The Heart tissue lysate of Mouse (30ug)
Lane 2: The Heart tissue lysate of Rat (30ug)
Lane 3: HuT78 whole cell lysate (6ug), Immunofluorescence analysis of MCF-7 cells using CD6 pAb at dilution of 1:200.

Alternative Name: T-cell differentiation antigen CD6; T12; TP120; CD6; Soluble CD6

Immunogen: Recombinant protein of human CD6.

Conjugate: Unconjugated

Modification: Unmodified