CD86 Monoclonal Antibody - BT-MCA3775

CD86 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3775-50, BT-MCA3775-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.

Research Areas: Immunology, Stem cells, Microbiology

Target Protein: CD86

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD86

Immunogen: Purified recombinant fragment of human CD86 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 52kDa

UniProt Accession: P42081

Synonyms: B70, B7-2, LAB72, CD28LG2, MGC34413, CD86

GeneID: 942

Research Use Only