Product Description

CD86 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40005-50, BS40005-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P42081

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD86 Antibody detects endogenous levels of total CD86

Bioworld Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD86 Rabbit monoclonal antibody at 1:500 dilution
Lane 1: Raji whole cell lysate (30ug)
Lane 2: HuT78 whole cell lysate (30ug)
Lane 3: The Lung tissue lysate of Mouse (30ug)
Lane 4: CT-26 whole cell lysate (30ug), Immunohistochemical analysis of paraffin-embedded human tonsil, using CD86 Antibody., Immunofluorescent analysis of K562 cells, using CD86 Antibody.

Alternative Name: CD86; B7-2; B70; CD28LG2; LAB72; MGC34413; CTLA4 counter receptor B72; CLS1; Ly58; MB7;

Immunogen: A synthesized peptide derived from human CD86

Conjugate: Unconjugated

Modification: Unmodified