CD87 Monoclonal Antibody - BT-MCA2333

CD87 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2333-50, BT-MCA2333-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Research Areas: Others

Target Protein: CD87

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1D1B11

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD87

Immunogen: Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 37kDa

UniProt Accession: Q03405

Synonyms: PLAUR, UPAR, URKR, U-PAR

GeneID: 5329

Research Use Only