CD8A Monoclonal Antibody - BT-MCA3028

CD8A Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3028-50, BT-MCA3028-100

Citations, Manuals and MSDS Available upon request.

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Immunology, Cancer

Target Protein: CD8A

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6A9A5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD8A

Immunogen: Purified recombinant fragment of human CD8A (AA: extra 22-182) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 25.7kDa

UniProt Accession: P01732

Synonyms: CD8, MAL, p32, Leu2

GeneID: 925

Research Use Only