Product Description

CD91 (Phospho-S4520) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64564-50, BS64564-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregμlated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell popμlations of the central nervous system. In addition to its usefμlness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granμlosa cells of the ovary.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: LRP-1, A2MR, APOER, CD91, LRP1, Msi 1, Msi1, MSI1H, Musashi homolog 1, Musashi-1, Musashi1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human CD91 around the phosphorylation site of Serine 4520.

Dilution: WB:1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD91 (Phospho-S4520) polyclonal antibody detects endogenous levels of CD91 protein only when phosphorylated at Ser4520.

Molecular Weight: ~ 85 kDa

Pathway: Regμlation of Microtubμle Dynamics,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q07954

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only