CD97 Monoclonal Antibody - BT-MCA2852

CD97 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2852-50, BT-MCA2852-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Research Areas: Neuroscience

Target Protein: CD97

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6D7E6

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CD97

Immunogen: Purified recombinant fragment of human CD97 (AA: extra 419-552) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 91.8kDa

UniProt Accession: P48960

Synonyms: ADGRE5, TM7LN1

GeneID: 976

Research Use Only