Product Description

CDA7L Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31506-50, RA31506-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1., induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line., miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation., subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction., subunit:Interacts with MYC and PSIP1., tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 49

Protein Molecular Weight (kDa): 49

Storage: -20°C/1 year

Human Gene ID: 55536

Human SwissProt Number: Q96GN5

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only