CDC27 Monoclonal Antibody - BT-MCA3820

CDC27 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3820-50, BT-MCA3820-100

Citations, Manuals and MSDS Available upon request.

Background: Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

Research Areas: Cell Biology

Target Protein: CDC27

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5C12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CDC27

Immunogen: Purified recombinant fragment of human CDC27 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 91kDa

UniProt Accession: P30260

Synonyms: APC3, HNUC, ANAPC3, CDC27Hs, D0S1430E, D17S978E,

GeneID: 996

Research Use Only