Product Description

CDC45 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31509-50, RA31509-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cell division cycle 45 (CDC45) Homo sapiens The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 62

Protein Molecular Weight (kDa): 62

Storage: -20°C/1 year

Human Gene ID: 8318

Human SwissProt Number: O75419

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only