Cdc6 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18249-20, A18249-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 63kDa
Observed Molecular Weight: 62kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 990
SWISS: Q99741
Alternate Names: CDC18L; HsCDC6; MGORS5; HsCDC18; Cdc6
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: CDC6
Research Use Only