Cdk9 Monoclonal Antibody - BT-MCA0334

Cdk9 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0334-50, BT-MCA0334-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Research Areas: Epigenetics and nuclear signaling; Cell biology; Microbiology; Immunology

Target Protein: CDK9

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Cell division protein kinase 9

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P50750; Mouse: Q99J95

Synonyms: CDK9; CDC2L4; TAK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine; threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit

GeneID: Human: 1025

Research Use Only