CDK9 Monoclonal Antibody - BT-MCA2353

CDK9 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2353-50, BT-MCA2353-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

Research Areas: Epigenetics and nuclear signaling, Cell biology, Microbiology, Immunology

Target Protein: CDK9

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B5A7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CDK9

Immunogen: Purified recombinant fragment of human CDK9 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 43kDa

UniProt Accession: P50750

Synonyms: TAK, C-2k, CTK1, CDC2L4, PITALRE

GeneID: 1025

Research Use Only