CDKN1C Monoclonal Antibody - BT-MCA3411

CDKN1C Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3411-50, BT-MCA3411-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.

Research Areas: Cell Biology

Target Protein: CDKN1C

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3E3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CDKN1C

Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 57kDa

UniProt Accession: P49918

Synonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C

GeneID: 1028

Research Use Only