Product Description

CEND1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65403-50, BS65403-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disμlfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1, 4, 5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecμlar target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Horse

Host: Rabbit

Applications: IHC-P

Alternate Names: BM88, BM88 antigen, Cell cycle exit and neuronal differentiation 1, Cell cycle exit and neuronal differentiation protein 1, FLJ90066, MGC34326, CEND_HUMAN

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human CEND1:4-100/149

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: CEND1 Polyclonal Antibody detects endogenous levels of CEND1 protein.

Molecular Weight: 15kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8N111

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only