CENPE Rabbit pAb - A15263

CENPE Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A15263-20, A15263-100

Citations, Manuals and MSDS Available upon request.

Background: Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 316kDa

Observed Molecular Weight: 270kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 1062

SWISS: Q02224

Alternate Names: KIF10; CENP-E; MCPH13; PPP1R61; CENPE

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle.

NCBI Alias: CENPE

Research Use Only