CENPI Polyclonal Antibody - BT-AP14894

CENPI Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14894-20, BT-AP14894-50, BT-AP14894-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13.

Research Areas: Epigenetics and nuclear signaling

Target Protein: CENPI

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Centromere protein I

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q92674; Mouse: Q8K1K4; Rat: Q63517

Synonyms: Centromere protein I;CENP-I;FSH primary response protein 1;Follicle-stimulating hormone primary response protein;Interphase centromere complex protein 19;Leucine-rich primary response protein

GeneID: Human: 2491

Research Use Only