Product Description

Centrin-2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67314-50, BS67314-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Centrins are small conserved microtubμle nucleating proteins localized to centrosomes, also known as microtubμle organizing centers (MTOC), in eukaryotic cells. Centrin-1 is associated with cells that have cilia and flagella, whereas centrin-2 and -3 are ubiquitously expressed and important in centrosome duplication during cell division, as well as the structure and function of the MTOC . Human centrin-2 has also been shown to localize to nuclear pores and to have a role in regμlation of mRNA export . The yeast ortholog of centrin-2, CDC31, plays a part in control of protein degradation and sensitivity to DNA damage .

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: CALT, CEN2, Centrin-2, Caltractin isoform 1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length protein of human Centrin-2

Dilution: WB (1/500 - 1/2000), IF/ICC (1/50 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Centrin-2 protein.

Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P41208

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only