CHAT Polyclonal Antibody - E-AB-93173

CHAT Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-93173-60, E-AB-93173-120, E-AB-93173-200 Citations, Manuals and MSDS Available upon request. Abbreviation: CHAT Target Synonym: CHAT; CHOACTASE; CMS1A; CMS1A2; CMS6 Research Areas: Cancer, Neuroscience Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: WB, IF Isotype: IgG Clonality: Polyclonal UNIProt ID: P28329 Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. Concentration: 1mg/mL Immunogen: Recombinant fusion protein of human CHAT Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000, IF 1:50-1:200 Calculated MW: 70kDa/74kDa/82kDa Observed MW: 70kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only