CHD3 Monoclonal Antibody - BT-MCA3628

CHD3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3628-50, BT-MCA3628-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Research Areas: Epigenetics and nuclear signaling, Immunology

Target Protein: CHD3

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 2G4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CHD3

Immunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 226kDa

UniProt Accession: Q12873

Synonyms: ZFH, Mi-2a, Mi2-ALPHA, CHD3

GeneID: 1107

Research Use Only