Product Description

CHD8 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31597-50, RA31597-100

Citations, Manuals and MSDS Available upon request.

Background: chromodomain helicase DNA binding protein 8 (CHD8) Homo sapiens This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-300

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 57680

Protein MW (KDa): 283

SWISS: Q9HCK8

Source: Rabbit

Research Use Only