Chitotriosidase Monoclonal Antibody - BT-MCA0337

Chitotriosidase Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0337-50, BT-MCA0337-100

Citations, Manuals and MSDS Available upon request.

Background: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Research Areas: Immunology

Target Protein: CHIT1

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Chitotriosidase-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13231; Mouse: Q9D7Q1

Synonyms: CHIT1; Chitotriosidase-1; Chitinase-1

GeneID: Human: 1118

Research Use Only