Product Description

Chk2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16661-50, BZ16661-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: O96017

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Chk2 in HeLa lysates; 293T lysates using Chk2 antibody., Immunohistochemistry analysis of paraffin-embedded Human testis using Chk2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of Chk2 in Hela using Chk2 antibody.

Alternative Name: CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

Immunogen: A synthesized peptide derived from human Chk2

Conjugate: Unconjugated

Modification: Unmodified