Product Description

CHPT1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65472-50, BS65472-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q8WUD6

Host: Rabbit

Reactivity: Human, Mouse, Rat,Chicken,Dog, Pig, Cow, Horse, Rabbit, Sheep,

Applications: WB

All Applications: WB=1:500-2000

Background: CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CHPT1 Polyclonal Antibody detects endogenous levels of CHPT1 protein.

Bioworld Molecular Weight: 50 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-CHPT1 at 1/1000 dilution

Alternative Name: AAPT1-like protein; Cholinephosphotransferase 1; chpt1; CHPT1_HUMAN; Diacylglycerol cholinephosphotransferase 1; hCPT1.

Immunogen: KLH conjugated synthetic peptide derived from human CHPT1:61-160/406

Conjugate: Unconjugated

Modification: Unmodified