CIB1 Monoclonal Antibody - BT-MCA2247

CIB1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2247-50, BT-MCA2247-100

Citations, Manuals and MSDS Available upon request.

Background: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Research Areas: Signal transduction

Target Protein: CIB1

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5A1F5E12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CIB1

Immunogen: Purified recombinant fragment of CIB1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q99828

Synonyms: CIB, KIP, KIP1, SIP2-28

GeneID: 10519

Research Use Only