Product Description

Cleaved-Caspase 6 p18 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16406-50, BZ16406-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellμlar apoptotic processes. Upon apoptotic stimμlation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, IHC-P, ELISA

Alternate Names: CASP6, MCH2, Caspase-6, CASP-6, Apoptotic protease Mch-2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Cleaved

Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 33 kDa, Observed MW: 20, 35 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P55212

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only