Product Description

Cleaved-Caspase 8 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3219-50, MB3219-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q14790

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 55 kDa; Observed MW: 43,57 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Caspase8 in K562, 3T3, MCF-7 and Jurkat lysates using Caspase8 antibody., Immunohistochemistry analysis of paraffin-embedded mouse Spleen Tissue using Caspase8 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of Caspase 8 in THP-1, rat Brain, Hela lysates using Caspase8 antibody., Western blot analysis of Caspase 8 in Jurkat, MOLT4 lysates using Caspase 8 antibody

Alternative Name: CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH

Immunogen: Recombinant Protein of Caspase-8

Conjugate: Unconjugated

Modification: Unmodified