Product Description

Cleaved Caspase-9 P37 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS80387-50, BS80387-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing resμlts in mμltiple transcript variants.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase-9, casp9, Caspase 9

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Cleaved

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Caspase 9 p37.

Dilution: WB, 1:500 - 1:1000 IHC, 1:100 - 1:200 IF, 1:100 - 1:500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cleaved Caspase-9 P37 polyclonal antibody detects endogenous levels of Cleaved Caspase-9 P37 protein.

Molecular Weight: ~ 37 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P55211

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only