CLN8 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16843-20, A16843-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 33kDa
Observed Molecular Weight: 33kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 2055
SWISS: Q9UBY8
Alternate Names: EPMR; TLCD6; C8orf61; CLN8
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: CLN8
Research Use Only