Coilin Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6428-20, A6428-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies) . Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 63kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 8161
SWISS: P38432
Alternate Names: CLN80; p80-coilin; Coilin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Neuroscience, Cell Type Marker, Neuron marker.
NCBI Alias: COIL
Research Use Only