Coilin Rabbit pAb - A6428

Coilin Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6428-20, A6428-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies) . Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Category: Polyclonal Antibodies

Applications: WB, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 63kDa

Observed Molecular Weight: 80kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 8161

SWISS: P38432

Alternate Names: CLN80; p80-coilin; Coilin

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Neuroscience, Cell Type Marker, Neuron marker.

NCBI Alias: COIL

Research Use Only