Product Description

COL2A1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2268-50, BT-MCA2268-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Research Areas: Signal Transduction

Target Protein: COL2A1

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7F2A11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: COL2A1

Immunogen: Purified recombinant fragment of human COL2A1 (AA: 1222-1487) expressed in mammalian.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 142kDa

UniProt Accession: P02458

Synonyms: AOM, ANFH, SEDC, STL1, COL11A3

GeneID: 1280

Research Use Only