Product Description

Connexin 45 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4416-50, ES4416-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: GJC1, GJA7, Gap junction gamma-1 protein, Connexin-45, Cx45, Gap junction alpha-7 protein

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human GJC1. AA range:231-280

Isotype: IgG

Target: Connexin-45

Specificity: Connexin 45 Polyclonal Antibody detects endogenous levels of Connexin 45 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Testis, Uterus,

Observed Band (KD): 45kD

Function: Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell
Similarity: Belongs to the connexin family. Gamma-type subfamily
Subunit: A connexon is composed of a hexamer of connexins

Subcellular Location: Cell membrane, Multi-pass membrane protein Cell junction, gap junction

Storage and Stability: -20°C/1 year

Gene Name: GJC1

Protein Name: Gap junction gamma-1 protein

Mouse Gene ID: 14615

Mouse SwissProt Number: P28229

Rat Gene ID: 266706

Rat SwissProt Number: A4GG66

Research Use Only