Product Description

CREB Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65907-50, MB65907-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Phosphorylation-dependent transcription factor that stimμlates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellμlar promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellμlar processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB, IHC

Alternate Names: Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein corresponding to human CREB.

Dilution: WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of CREB protein.

Molecular Weight: ~ 43 kDa

Pathway: Signaling Pathways Activating p38 MAP Kinase, MAPK Erk in Growth and Differentiation Pathway, ErbB HER Signaling, T cell receptor signaling, Inhibition of Apoptosis, Dopamine Signaling in Parkinson\'s Disease Plathway,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16220

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only