Crk-L Monoclonal Antibody - BT-MCA0388

Crk-L Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0388-50, BT-MCA0388-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Research Areas: Epigenetics and nuclear signaling; Neuroscience; Signal transduction; Cancer

Target Protein: CRKL

Applications: WB, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Crk-like protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P46109; Mouse: P47941

Synonyms: CRKL; Crk-like protein

GeneID: Human: 1399

Research Use Only