Crk-L Polyclonal Antibody - BT-AP02235

Crk-L Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02235-20, BT-AP02235-50, BT-AP02235-100

Citations, Manuals and MSDS Available upon request.

Background: CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Research Areas: Neuroscience

Target Protein: CRKL

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Crk-L Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 33777

UniProt Accession: Human: P46109; Mouse: P47941; Rat: Q5U2U2

Synonyms: CRKL; Crk-like protein

GeneID: Human: 1399; Mouse: 12929; Rat: 1.00911e+008

Research Use Only