Product Description

CRSP77 (V171) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2368-50, BS2368-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CRSP is ubiquitously expressed in various tissues and functions as a mμltimeric complex that consists of nine distinct subunits, each having an individual molecμlar mass ranging from 33 to 200 kDa. Several members of the CRSP family share sequence similarity with mμltiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger mμltimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC

Alternate Names: Mediator of RNA polymerase II transcription subunit 17, Activator-recruited cofactor 77 kDa component, ARC77, Cofactor required for Sp1 transcriptional activation subunit 6, CRSP complex subunit 6, Mediator complex subunit 17, Thyroid hormone receptor-associated protein complex 80 kDa component, Trap80, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component, DRIP80, MED17, ARC77, CRSP6, DRIP77, DRIP80, TRAP80

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 140-190 of Human CRSP77.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CRSP77 (V171) polyclonal antibody detects endogenous levels of CRSP77 protein.

Molecular Weight: ~ 73 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NVC6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only