CSK22 Polyclonal Antibody - BT-AP15113

CSK22 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15113-20, BT-AP15113-50, BT-AP15113-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.,Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.,Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.,

Research Areas: Signal transduction

Target Protein: CSNK2A2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Casein kinase II subunit alpha'

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P19784; Mouse: O54833

Synonyms: Casein kinase II subunit alpha';CK II alpha';EC 2.7.11.1

GeneID: Human: 1459

Research Use Only