Cyclin A1 (R436) Polyclonal Antibody-BS1084

Cyclin A1 (R436) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1084-50, BS1084-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P78396

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Cyclin A1 (R436) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 52 kDa

Specificity: Cyclin A1 (R436) polyclonal antibody detects endogenous levels of Cyclin A1 protein.

Alternative Name: Cyclin-A1; CCNA1; Cyclin A1; CyclinA1;

Immunogen: Synthetic peptide, corresponding to amino acids 400-450 of Human Cyclin A1.

Conjugate: Unconjugated

Modification: Unmodified