Cyclin E2 Polyclonal Antibody-BZ16704

Cyclin E2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16704-50, BZ16704-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: O96020

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Background: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cyclin E2 in HeLa lysates using Cyclin E2 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using Cyclin E2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of Cyclin E2 in Hela using Cyclin E2 antibody.

Alternative Name: CCNE2; G1/S-specific cyclin-E2

Immunogen: A synthesized peptide derived from human Cyclin E2

Conjugate: Unconjugated

Modification: Unmodified