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Cyclin H (E311) Polyclonal Antibody - BS2437

Cyclin H (E311) Polyclonal Antibody - BS2437

Regular price $274.50 CAD
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Cyclin H (E311) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2437-50, BS2437-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cyclin H belongs to the highly conserved cyclin family, and are regμlators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC, IF

Alternate Names: Cyclin-H, MO15-associated protein, p34, p37, CCNH

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human Cyclin H.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cyclin H (E311) polyclonal antibody detects endogenous levels of Cyclin H protein.

Molecular Weight: ~ 38 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51946

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only

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