CYLD Polyclonal Antibody - BT-AP08253

CYLD Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08253-20, BT-AP08253-50, BT-AP08253-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Tags and cell markers

Target Protein: CYLD

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ubiquitin carboxyl-terminal hydrolase CYLD

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9NQC7; Mouse: Q80TQ2; Rat: Q66H62

Synonyms: Ubiquitin carboxyl-terminal hydrolase CYLD;EC 3.4.19.12;Deubiquitinating enzyme CYLD;Ubiquitin thioesterase CYLD;Ubiquitin-specific-processing protease CYLD

GeneID: Human: 1540

Research Use Only