CYP17A1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13968-20, A13968-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Rat
Protein Weight: 57kDa
Observed Molecular Weight: 57kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1586
SWISS: P05093
Alternate Names: CPT7; CYP17; S17AH; P450C17; CYP17A1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Mitochondrial metabolism, Lipid Metabolism, Lipases, Cardiovascular, Lipids.
NCBI Alias: CYP17A1
Research Use Only