DACA-1 Polyclonal Antibody - BT-AP02493

DACA-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02493-20, BT-AP02493-50, BT-AP02493-100

Citations, Manuals and MSDS Available upon request.

Background: The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. YTHDF2, also designated High-glucose-regulated protein 8, CLL-associated antigen KW-14 or Renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain. YTHDF3 is a 585 amino acid protein that also contains one YTH domain. The gene encoding YTHDF1 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Research Areas: Cell Biology

Target Protein: YTHDF1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DACA-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 60874

UniProt Accession: Human: Q9BYJ9; Mouse: P59326

Synonyms: YTHDF1; C20orf21; YTH domain family protein 1; Dermatomyositis associated with cancer putative autoantigen 1; DACA-1

GeneID: Human: 54915; Mouse: 228994

Research Use Only