DAG1 Polyclonal Antibody - BT-AP08370

DAG1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08370-20, BT-AP08370-50, BT-AP08370-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

Research Areas: Neuroscience; Signal transduction

Target Protein: DAG1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dystroglycan

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q14118; Mouse: Q62165

Synonyms: Dystroglycan;Dystrophin-associated glycoprotein 1 [Cleaved into: Alpha-dystroglycan;Alpha-DG; Beta-dystroglycan;Beta-DG]

GeneID: Human: 1605

Research Use Only