Product Description

DDC Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92553-60, E-AB-92553-120, E-AB-92553-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DDC

Target Synonym: DDC; AADC

Research Areas: Neuroscience,Cancer,Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P20711

Background: The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human DDC

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000, IHC 1:50-1:200, IF 1:50-1:200

Calculated MW: 37kDa/44kDa/45kDa/53kDa

Observed MW: 37KDa/54KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only