DDX8 Polyclonal Antibody - BT-AP02553

DDX8 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02553-20, BT-AP02553-50, BT-AP02553-100

Citations, Manuals and MSDS Available upon request.

Background: DHX8 is a member of the DEAH box polypeptide family. DEAH-box helicase 8 contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: DHX8

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DDX8 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 139315

UniProt Accession: Human: Q14562; Mouse: A2A4P0

Synonyms: DHX8; DDX8; ATP-dependent RNA helicase DHX8; DEAH box protein 8; RNA helicase HRH1

GeneID: Human: 1659; Mouse: 217207

Research Use Only